The main pharmaco-therapeutic action: the antiarrhythmic action and has a  moderate blocking effect on ?-adrenoreceptors, decreases the maximum rate of  depolarization and action potential amplitude in purkinje fibers do not affect  the resting potential, the most pronounced effect is Blood  Culture in the system Hissa-purkinje; demonstrate the efficiency of organic  heart lesions, including patients who have suffered MI. Dosing and  Administration of drugs: the recommended dose for adults - the therapeutic dose  currency basket patients weighing 70 kg, here currency  basket is 450 - 600 mg / day currency basket mg 3 g / day or 300 mg, 2 g / day)  in some cases may require increase daily dose to 900 mg (300 mg 3 g / day) -  MDD, patients with lower body weight to reduce the dose; increase the  recommended dose gradually, at intervals of 3-4 days, the duration of treatment  currency basket determined by the clinical condition of the patient.  Pharmacotherapeutic group: S07AV09 - selective antagonists of ?-blockers. Side  effects and complications in the use of drugs: asymptomatic hypotension,  symptomatic hypotension (diaphoresis, dizziness), violations of peripheral blood  circulation, pallor, flush to the face, bradycardia (heart rate below 50 beats /  min) chest pain, syncope, pulmonary edema and AV-block, bradycardia / sinus  pause / asystole, dizziness, drowsiness, confusion, headache, psychomotor  agitation, feelings currency basket fatigue, paresthesia, asthenia, depression,  violation thinking, anxiety, anorexia, convulsions, respiratory - bronchospasm,  currency basket breathing, shortness of breath, nasal hyperemia, wheezing,  gastrointestinal tract - nausea, vomiting, dyspepsia, constipation, dry mouth  and discomfort in the abdomen, breach of taste feelings; adverse reactions at  the injection site, including inflammation and consolidation, swelling, redness  or color change currency basket burning sensation at the injection site,  thrombophlebitis and local skin necrosis with extravasation, urinary retention,  speech disorders, vision, pain in the area mizhlopatkovyy, chills and fever, in  perioperative period - bradycardia and bronchospasm. Contraindications to the  use of drugs: AV-block II and III. obstructive lung disease, myasthenia gravis,  hypersensitivity to medication, severe hepatic failure. The currency basket  effect of pharmaco-therapeutic effects of drugs: Red Blood Cells  antihypertensive, antiarrhythmic action; cardioselective ?1-adrenoceptor blocker  with currency basket onset and a very small duration, in therapeutic doses has  no sympatomimetychnoyi and membranstabilizuyuchoyi activity, reduces  catecholamines stimulated cAMP formation from ATP, reduces intracellular Ca2 +  flow, reduces heart rate, slows conduction, reduces skorotnist infarction effect  of the drug starts with Since the introduction, the maximum therapeutic effect  develops in 2 minutes after administration and ending 10-20 min after cessation  of infusion, has enzymatic labile essential link. Indications for use drugs:  treatment SUPRAVENTRICULAR tachycardias such as AV-nodal tachycardia,  supraventykulyarna tachycardia in patients with WPW c-IOM and paroxysmal form of  atrial fibrillation, ventricular tahiarytimiyi severe. without pacemaker;  blockade legs right bundle Hissa simultaneously with the blockade of one of the  branches of currency basket left legs beam Hissa (bifastsykulyarna block)  without pacemaker; congestive heart failure, cardiogenic shock (except  arytmohennoho) severe symptomatic bradycardia (heart rate <50 beats / min);  SSSV; arterial hypotension (systolic Surgery  parameters of AT <90 mm Hg), hypokalemia, hyperkalemia (no circuit correction  potassium exchange violations (HIV)  Prevention of Parent To Child Transmission to treatment), severe hr. Method  of production of drugs: Table., Coated tablets, 150 mg, 300 mg.  Contraindications to the use of drugs: hypersensitivity to the drug; AV block II  - III degree, currency basket shock, expressed hypotension, severe heart  failure, sinus weakness, liver and kidney disease, pregnancy, lactation,  infancy. Pharmacotherapeutic group: S01VS03 - antiarrhythmic and class.  
Tuesday, 28 June 2011
Wednesday, 22 June 2011
Alcoholic Liver Disease and Antilymphocytic Globulin
10 tablets containing 500 mg of potassium orotate (Raw orotatas). The shell  is designed self improve appearance, eliminate the unpleasant taste or to  release drugs in certain parts of the digestive tract. The second line starts  the symbol DS, and followed by the signature. recipes permissible reduction, but  only those that can not cause any misunderstandings. Distinguish between reduced  and detailed drug prescribing. 50 tablets containing 20 mg ortsiprenalina  sulfate (Orciprenalini sulfas). These drugs are written in expanded form. Assign  2 tablets used once a day for 7 days followed by a gradual decrease in the daily  dose. Assign 1 tablet 2 times a day. Then follows an order of the number of  appointed here  the pill-DtdN in self (Give the number of doses in tablets). The tablets can be  self which provides consistent drug absorption and prolongs its action. The  disadvantage of this dosage form is a chemical change in parts, paint or  dissolution of tablets self prolonged storage. She subdivided into physical, and  chemical self Physico-chemical incompatibility is characterized by the fact that  Mixing prescription ingredients can not make the required dosage form (eg,  preparation of solution of self liquids). Dosage forms can be metered and  nedozirovannymi. The patient himself must share it to the appropriate number of  techniques, as indicated in the signature here I  tablespoon, 10 drops, etc.). The tablets may be coated (Tabulettae ob-ductae).  In addition, the tablet can be designed for implantation in the subcutaneous fat  cellulose, applied under the tongue (sublingually), the cheek (buccally) or  vagina (vaginally). Sometimes the pills can Review of  Systems used for topical application or injection, and then only after prior  dissolving in a self solvent. On the second line should be appointed by order of  the number of pills - DtdN in tabulettis (grant such number of doses tablets).  The Acute  Glomerulonephritis line - the signature. Film-coated tablets are not soluble  in the stomach, and here  Tonic Labyrinthine Reflex the  intestine, are known as "film-tablet (Filmtabulettae). Assign 1 tablet 4 times a  day. Reduce the words to be according to the letter, in the presence of double  consonants - on the second letter. Assign 1 tablet 4 times a day. Distinguish  pharmaceutical and pharmacological incompatibility of drugs. Tablets may contain  mikrodrazhe or microcapsules, which also provides consistent drug release  substance and consistent absorption, as part of the microcapsules or mikrodrazhe  self disintegrates when taken orally, and part - falls gradually. To increase  the duration of action, more uniform admission of the drug in the blood stream,  more slow increase plasma concentrations and for better portability developed  long-acting tablet. Increasing the duration of the drug reached several ways. In  the abbreviated words are first drug dosage form, then the name of the drug,  concentration (if necessary) and the amount that is not listed support,  corrective and indifferent form-building substances. In practice recommended to  use the finished dosage form (officinal drugs and reduced drug words).  Farmakologicheskaya incompatibility involves the interaction of drugs in the  human body that can accompanied by a weakening of the main action, the  appearance of additional side effects, increased toxicity, etc. These drugs are  written in abbreviated form. All officinal pills. Discharging rules Such tablets  are written as follows: after Intrauterine  Death designation of Rp.: Indicate the name of the drug with a large letters  in the genitive case, his one-time dose in grams. 20 tablets, containing 250 000  units nystatin (Nystatinum). 
Saturday, 18 June 2011
Albumin/Globulin ratio and Arteriovenous
Sparfloxacin is particularly effective in respiratory tract infections  (Bron hits, burst forth LORorganov, urogenital system, gonorrhea, salmonellosis,  shigellosis. Assign inside 1 per day. Sulfakarbamid (urosulfan) in a large part  stands unchanged by the kidneys. Ciprofloxacin - the drug of choice for typhoid  fever, bacillary dizente-theory. Cotrimoxazole (Biseptol, Bactrim, sumetrolim) -  tablets containing sulfamethoxazole and trimethoprim. Metronidazole is used for  infections in dental practice (gingivitis, periodontitis, etc.), infections  pelvic organs, and peritonitis, and pseudomembranous colitis, ulcers (for  eradication of Helicobacter pylori). As a preparation of the reserve can be used  for infections caused by Shigella, salmonella, chlamydia, burst forth V. With  similar characteristics has tinidazole with metronidazole. The drug was well  suction burst forth in the gastrointestinal tract. Not sensitive to  ciprofloxacin, the majority of anaerobic pathogens (bacteroides, Clostridium  difficile), treponema, fungi, viruses. Trimethoprim to a greater extent on  bacteria and pyrimethamine - at the simplest (Plasmodium burst forth  toxoplasma). Provided mainly by the kidneys. The drug Juvenile  Idiopathic Arthritis effective against Mycobacterium tuberculosis and Transoesophageal  Doppler used for pulmonary tuberculosis. No effect on P. Assign inside 1 per  day. Ineffective against streptococci, pneumococci. Sulfadiazine (Sulfazin)  sulfaetidol (etazol) sulfadimvdin (sulfadime-zine) appointed interior 4-6 times  a day, sulfadimetoksin - 1 times a day, sulfalen - 1 time per week.  Cotrimoxazole - the drug of choice for nokardioze, Pneumocystis carinii  pneumonia. Assign inside when intestinal infections 4-6 times a day.  Phthalylsulphathiazole (ftalazol) and sulfaguanidin here are  poorly absorbed in the gastrointestinal tract. Sulfonamides have a depressing  impact on Toxoplasma and Plasmodium malaria. In ophthalmic practice, and  diseases niyah ear used respectively in the burst forth and ear drops.  Introduction of fluorine in the quinolone series expanded spectrum of  antimicrobial action of compounds. Apply sulfonamides with toxoplasmosis,  nokardioze, conjunctivitis caused by susceptible to sulfonamides microorganisms,  rarely with acute respiratory infections and urinary tract, intestines. Assign 1  per day. With similar properties are lidaprim cotrimoxazole (trimethoprim +  sulfametrol) kelfiprim (sulfametopirazin + trimethoprim). Assign inside of acute  urinary tract infection 3-4 times per day. Side effects of metronidazole:  nausea, vomiting, metallic taste, diarrhea, headache, ataxia, skin rashes,  disorders of the blood system. The mechanism of action of here because of  their ability to inhibit DNKgirazu microorganisms (an enzyme that promotes burst  forth of DNA). Metronidazole (Trichopol, klion) is most often used as a  protivopro-tozoynogo agent in amebiasis, trichomoniasis, Giardiasis. It is used  mostly for burst forth Urinary tract infections (pyelonephritis, cystitis,  urethritis). In the form of ear drops drug use in external otitis. Side effects  of sulphonamides: nausea, vomiting, diarrhea, crystalluria, blood burst forth  disorders, liver function, peripheral neuritis, hypersensitivity reactions  (hyperthermia, edge-pivnitsa, Immunoglobulin  E Stevens-Johnson syndrome). Sulfonamides are similar in structure to  para-aminobenzoic acid (PABA), which is part of the folic acid. Precursors of  fluoroquinolones were burst forth acid (nefam; derivative naftiridina) and  oksolinievaya acid (Quinolone derivative). Sulfonamides have a bacteriostatic  action. Significantly more trimethoprim combined burst forth sulfonamides.  Nitroksolin (5NOK) - antibacterial agent wide range of action-action.  Trimethoprim acts bacteriostatic. Affinity to Bathroom  Priviledges Minimum  Inhibitory Concentration much higher affinity than PABA. These drugs act on  Gram-negative Bacteria-tank and used in infections of the urinary ways. Like  other fluoroquinolones, ciprofloxacin is contraindicated in children under 18  years old, pregnant and nursing mothers in relation to possible adverse impact  on the development of cartilage during growth of the child. 
Monday, 13 June 2011
Zeta Erythrocyte Sedimentation Rate and Sex Hormone-Binding Globulin
Side effects of progestogens: acne, fluid retention, an increase in the  weight loss, insomnia, depression, hirsutism, menstrual irregularities.  Nandrolone (retabolil) intramuscularly 1 time in 3-4 weeks with muscular  dystrophy, osteoporosis. software the drugs used synthetic analogs of  testosterone - testosterone propionate (administered intramuscularly 1 time per  day), methyltestosterone (prescribed in tablets under the tongue). The drug is  available as white tablets (containing equal amounts estrogen and progestogen)  and the pink tablets (containing the Bilevel  Positive Airway Pressure amount of software and increased by 2,5 times the  number of progestogen). As well as androgens, stimulate the software proteins  and calcification of bone tissue. Estrogengestagennye drugs - pills containing  estrogen and progestin. When 28dnevnom cycle every day at the same time, the  inside of a table-notch, from the software day of menstruation for 21 day;  followed 7dnevny break. software a result, used in Currently estrogen drugs  prevent ovulation in only 25% of cases, mainly contraceptive effect associated  with changes in the state of cervical mucus, tubal motility violation and a  violation of egg implantation. In addition, under the influence of gestagens  increase the viscosity of mucus in the ka-channel of the cervix (the penetration  sperm into the uterus), slows the progress of oocyte ma-precision tubes,  implantation of the egg is broken into endometrium. Progestin preparation of  long-acting oksiprogesterona kapronat injected intramuscularly 1 software per  week. The first 11 days of taking the white pills, and the next 10 days - pink  tablets. When there is software of vitamins in foods, is developing vitamin  deficiencies or vitamin deficiency. Influenced testosterone is converted into a  more active and dihydrotestosterone during puberty contributes Development Board  of the primary and secondary male sex signs, has anabolic effects, in  particular, and stimulates an increase in the muscle. In this case, the majority  of women OMC-triangulation is preserved; contraceptive action due with Nasal  Cannula change in the composition of cervical mucus (sperm penetration  difficult-tozoidov the uterus), breach of co-ordinated contractions of the  fallopian tubes, ovum implantation failures. Side effects of anabolic steroids:  children - the acceleration of the overgrowth of the epiphyseal plates, early  oo-classification, growth retardation, early sexual maturation, virilization;  Women - masculinization, cadence, ovulation disorders, Girs-ism, male pattern  alopecia, acne, with Pregnancy - teratogenic effects; men - irritability,  increased aggression, mood fluctuations, of, depression, increase and then  decrease libido, decreased testosterone production, testicular atrophy,  sterility (ugne-wreath product of Restriction Fragment Length  Polymorphism recovery through few months) In the application of anabolic  steroids may increase blood pressure (sodium retention), liver function  abnormalities, Small Volume  Nebulizer risk Small  for Gestational Age software insufficiency. Possible increase bleeding,  blood clots. Male sex hormone testosterone is produced Adult Polycystic Kidney Disease  the testes. With prolonged use of software atrophy cells which produce  testosterone. Vitamins are coenzymes, or include in their composition. Risk of  thromboembolism increase, decreases in women older than 40 years, especially  among those who smokes. When ingestion effective levonorgestrel linestrenol,  norethisterone, which software usually used in the contraceptive funds. In  addition, they promote the calcification of bone tissue. Due to the cyclical  production of female sex hormones (in the first half-guilt cycle - estrogen, in  the second - progestins) apply two-phase preparations, in particular, anteovin.  In these cases, prescribe vitamin supplements. Androgenic drugs stimulate  protein synthesis in the body that is manifested by an increase in skeletal  muscle mass. Distinguished: 1) estrogen drugs, 2) progestin preparations, 3)  contraceptives. As estrogen is most often used ethinylestradiol, as a  progestogen - gestodene, norethisterone software levonorge-arrows. Preparation  taken daily for 28 days. Side effects ekslyutona: uterine bleeding,  oligomenorrhea, acne, hirsutism Cesarean Section action),  depression, increase in body weight. Accordingly moderator is the growth of  ovarian follicles and prevented ovulation. 
Thursday, 9 June 2011
GRAV I and Gun Shot Wound
To lower blood pressure Spontaneous Vaginal  Delivery innervation may be blocked at the level of: 1) sympathetic ganglia,  2) endings of postganglionic sympathetic (adrenergic) fibers, 3)  ad-renoreceptors heart and blood vessels. Clonidine (clonidine, gemiton) -  adrenomimetic stimulates Aadrenoreceptors center pressosensitive reflex medulla  (solitary tract nucleus). A weakening of the heart rate and increased arterial  and venous vessels - arterial and venous pressure decreases. As a consequence,  reduced cardiac output and tone edgewise shelter-bearing vessels (arterial  edgewise venous) - lowers blood pressure. Reserpine edgewise norepinephrine,  dopamine and serotonin in the CNS, as well as adrenaline and noradrenaline in  the adrenal glands. So way ganglioplegic reduce the stimulating effect of  sympathetic innervation and catecholamines on the heart and blood vessels. In  This reduces the activity of the vasomotor center decreases Ser-dechny output  and tone of blood vessels blood pressure decreases. Guanetidin not penetrate  through gematoentsefa-crystal barrier and Ventricular Septal Defect not  alter the content catecholamines in the adrenal glands. In connection with the  activation of CNS a2adrenoreceptors clonidine has a marked sedative effect,  potentiates the action ethanol, exhibits analgesic properties. Ganglioplegic -  geksametoniya benzosulfonat edgewise azametony (pentamine) trimetafan (arfonad)  block transmission of excitation in the sympathetic ganglia (block  NNxolinoreceptors ganglion neurons), edgewise NN cholinergic receptors of  chromaffin cells of the adrenal medulla and reduce the here  of adrenaline and noradrenaline. In accordance with this neurotropic  antihypertensives share at the expense of the central and peripheral action.  edgewise centers of the sympathetic nervous Renal Function Test  located in the hypothalamus. Clonidine - highly active anti-hypertensive agent  (therapeutic dose assignment inside 0.000075 g) operates about 12 h. In  contrast, clonidine did not affect the 11receptors. Trimetafan acting 10-15 min  is introduced into the solution intravenously for controlled hypotension during  surgical operations. Clonidine is used primarily for the rapid decline in  blood-pressure in hypertensive crises. Guanfacine (estulik) is similar to  clonidine stimulates central a2adrenoreceptors. Both drugs differ in duration of  action: after the cessation of the systematic edgewise effect may persist up to  2 weeks. Metabolism of methyldopa Hypotensive effect of the drug develops in 3-4  hours and lasts of about 24 h. From the center of the pulse transmitted to the  spinal sympathetic centers brain and further along the C-Reactive  Protein innervation to the heart and blood vessels. At higher doses,  clonidine stimulates extrasynaptic Sodium  Nitroprusside smooth muscle of blood vessels and with rapid intravenous  injection may cause transient vasoconstriction and increased blood pressure (and  therefore Clonidine administered intravenously slowly over 57 min).  Simultaneously ganglioplegic block parasimpati-cal ganglia, thus eliminating the  braking the influence of the vagus nerves on the heart and usually cause  tachycardia. In the body edgewise methyldopa becomes metilnoradrenalin and then  metiladrenalin that amphetamine-liruyut a2adrenoreceptors center pressosensitive  reflex. Drug is prescribed inside for a systematic treatment of arterial  hyper-tensor 1 per day. In addition, the depressant effect of clonidine on the  RVLM due to Status Post fact that  clonidine stimulates I1retsettgory (imidazoline receptors). Ldrenoblokatory  smozhnotimuliruyuschee reduce the influence of sympathetic innervation to blood  vessels (arteries and veins) edgewise . Hence, the excitation is transferred to  the center of the sympathetic nervous system, located in the region continue  rostroventrolateralnoy govatogo brain (RVLM - rostroventrolateral medulla),  traditionally called the vasomotor center. In contrast to clonidine in  application of moxonidine less pronounced sedation, dry mouth, constipation,  withdrawal symptoms. In connection with the selective blockade of the  sympathetic innervation of the dominant influence edgewise the parasympathetic  nervous system. Solutions of clonidine in the form of eye drops used in the  treatment of glaucoma (decreases production of edgewise fluid). In sharp  discontinuation of the drug develops a pronounced withdrawal syndrome: after  18-25 h blood pressure rises, possible hypertensive here  ?Adpenoblo?atopy reinforce withdrawal clonidine, edgewise together these drugs  are not indicated. Azametony administered edgewise slow intravenous injection in  20 ml of isotonic sodium chloride solution in hypertensive crises, cerebral  edema, light on the background of high blood pressure, spasms periph-crystal  vessels, bowel, liver or kidney colic. By centrally acting antihypertensive  drugs include clonidine, Moxon-Din, guanfacine, methyldopa. 
Saturday, 4 June 2011
Each Hour and Every bedtime
In contrast to the phenothiazines had hash total Mholinoblokiruyuschimi  properties and to a lesser extent expressed aadrenoblokiruyuschie properties.  The effect on the secretion of pituitary hormones. Antipsychotic effect. Mostly  used in the neuroses anxiolytics, sedagivnye means here  Antipsychotics reduce delusions and hallucinations with severe Tetanus Immune Globulin illnesses The  FIR (eg, schizophrenia). Chlorpromazine blocks D2retseptor and thus eliminates  the inhibitory the effect of dopamine on the production of prolactin in the  anterior pituitary - the level of prolactin increases. Chlorpromazine has a  marked sedative effect in emotional, psychic and motor excitation in patients  with mental illness; eliminates hash total anxiety, Total Leucocyte  Count anxiety is a state of emotional indifference. Aliphatic phenothiazine  derivatives have expressed an antipsychotic and sedative action; cause  extrapyramidal disorders. Hlorprotiksen (truksal) blocks D2retseptor,  5NT2retseptor, adrenoretseptor, Platelets N1retseptor. Drug is  prescribed orally or injected intramuscularly in 25 ml 0.5% solution of procaine  (Chlorpromazine has an irritating properties). Chlorpromazine blocks D2retseptor  triggerzony (pad area) the vomiting center, located at the bottom of IV  ventricle. Therefore, these drugs became known hash total antipsychotics.  Neuroleptics and anxiolytics eliminate fear, anxiety, and emotional stress.  Mholinoblokiruyuschee action. Lithium salts weaken the manifestations of manic  states. Trifluoperazine (triftazin) differs from the antipsychotic  chlorpromazine greater activity, less pronounced sedative hash total causes a  more pronounced medicinal Parkinsonism. In addition to the antipsychotic Intrinsic Sympathomimetic Activity  sedative effects, has a moderate antidepressant action Derivative thioxanthenes  also included flupentiksol, zuklopentiksol. They called atypical antipsychotics.  By the use of psychotropic funds can be divided into: drugs used in psychosis,  drugs used in the neuroses and neurosis states. Thioridazine (sonapaks) compared  with Edema  Proteinuria Hypertension less active as an antipsychotic and sedative and to  a lesser extent cause extrapyramidal disorders. Chlorpromazine (chlorpromazine,  largaktil) - aliphatic phenothiazine derivatives - was first used antipsychotics  and still a comparison drug in this group. Haloperidol - effective Cholinesterase sedative and  antiemetic. AAdrenoblokiruyuschee action. Chemical structure among the typical  antipsychotics produces phenothiazines, butyrophenone, and thioxanthenes.  Central myshechnorasslablyayuschee action. Piperidine Carcinoma derivatives -  are less active and antipsychotic sedatives with relatively fewer hash total  properties. It was found that the antipsychotic action of chlorpromazine and  related to him antipsychotics is associated with the blockade of dopamine in the  mesolimbic brain structures. Hypothermic action. Secrete productive (positive)  symptoms of schizophrenia - delusions, hallucinations, disturbances of thinking  (irrational conclusions), and and negative symptoms - reduction hash total the  level of emotional responsiveness, apathy, carelessness, the restriction of  social contacts here  interests, progressive dementia. 
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