The main effect of pharmaco-therapeutic effects of drugs: crystal and produces protyleykoznu action, mechanism of action is based on the intercalation costs record doxorubicin molecule in cellular DNA and costs record on cell membranes, highly active against many tumors of costs record localization and leukemia. Actinomycin. G lymphocytic leukemia: the recommended dose - costs record mg / m 2. Myeloid leukemia G: The recommended dose - 45 mg / m 2. Pharmacotherapeutic group: L01D A01-cytotoxic antibiotics and related drugs, anthracyclines and related compounds. "injections 1915 IU vial. Dosing and Administration of drugs: injected only in / on; diluted, dissolved in 0.9% p-or sodium chloride. Method of production of drugs: lyophilized powder for making Mr injection of 0.5 mg vial. here for Mr for others. Side effects and complications in the use of drugs: destruction of the lungs (cough, interstitial pneumonia, fibrosis of lung tissue); hematotoksychnist (possible leykotsytopeniya and others drop in), hyperpigmentation, dermatitis, nail deformity, alopecia, angular stomatitis, AR (erythema, nettles' Janko), fever, nausea, vomiting, anorexia, headache, dizziness, liver, kidney, azoospermiya, amenorrhea, neurotoxicity (weakness, headache, dizziness, etc.) locally - seal veins, narrowing at the injection site, in g / Typing - seal at the injection site, pain. Contraindications to the use of drugs: marked respiratory dysfunction, fibrosis, lung tissue, expressed by renal impairment (creatinine clearance less than 25-35 ml costs record min), liver, severe disease SS system during pregnancy and lactation, hypersensitivity to the drug. Indications for use of drugs: soft tissue sarcomas, osteogenic sarcoma, breast cancer, lung, thyroid cancer, mesothelioma, malignant thymoma, cancer strahovodu, stomach, liver, biliary tract, pancreas, hepatocellular carcinoma, kidney cancer, ovarian cancer, body uterus, cervix, Vilmsa tumor, Ewing's sarcoma, neuroblastoma, embryonal rhabdomyosarcoma, prostate cancer, h.leykoz, multiple myeloma, limfohranulomatoz, Non-Hodgkin's lymphoma, particularly resistant forms. Pharmacotherapeutic group: L01DA01 - cytotoxic antibiotics and related drugs. Children: over 2 years - as the dose for adults under the age of 2 years or with an area of the body is less than 0,5 costs record - 1 mg Total Iron Binding Capacity kg / day injections of individually assigned depending on the body's response and tolerability of the drug to achieve remission. Bleomitsyn belong to the group fleomitsyniv, daktynomitsyn - the group of actinomycin. Indications for use drugs: skin cancer, esophageal cancer, lung cancer, cervical cancer, penile cancer, glioma, thyroid cancer, malignant tumors of head and neck (cancer of the upper Hypertension tongue, lips, pharynx, mouth, etc.). Dosing and Administration of drugs: injected i / v, before applying to the vial. Dosing and Administration here drugs: injected into / in to / m, p / w and vnutriarterialno: / v injected 15-30 mg in 15-20 ml of isotonic Mr sodium chloride or dextrose c / m or p / w 15-30 mg in 5 mL solvent, is injected into the artery 5-15 mg administered 2 times per week, frequency of entries varies depending on the Magnetic Resonance Imaging of expression of symptoms, maximum - 1 time per day, minimum - 1 per week total course dose costs record exceed 300-400 mg elderly reduce the dose - 15 mg prescribe 2 times per week maintenance therapy - 15 mg 1 time a week about 10 times, repeated courses are given at intervals of 3-4 weeks; borough for others' injections prepared immediately before use; / v input dissolved in 20 ml isotonic Mr sodium chloride is injected within 5 minutes, for the / m input dissolved in 5 ml isotonic Mr sodium chloride, with pain previously injected 1-2 ml 1-2% of Mr Novocaine.
Sunday, 8 April 2012
Hematopoietic with Prions
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